Description

COMPOSITION:

Contains per g: Piperazine dihydrochloride 1,000  mg

DESCRIPTION:

Piperazine dihydrochloride is an anthelmintic for use in drinking water or feed. Piperazine dihydrochloride is a hygroscopic, alkaline chemical, well soluble in water. Piperazine is a selective agonist of gamma-amino butyric acid (GABA) receptors, resulting in the opening of chloride channels and hyperpolarisation of the membrane of the muscle cells of the nematode parasite. The hyperpolarisation causes nerve membranes to block at the neuromuscular junction, causing paralysis to the nematodes which are then excreted with the faeces.

INDICATIONS:

Piper Dewormer wsp is a narrow-spectrum anthelmintic against infestations with roundworms (Nematodes) in poultry, cattle, horses and pigs. It has no effect on lungworms and on larval stages of Ascaris worms.

• Poultry : Ascaridia spp.
• Cattle : Ostertagia, Haemonchus, Trichostrongylus and Oesophagostomum spp.
• Horses : Parascaris equorum
• Pigs : Ascaris suum and Oesophagostomum spp.

CONTRA-INDICATIONS:

Dot not administer to animals with a severe impaired liver or kidney function. Do not administer to animals hypersensitive to piperazine. Do not combine with organic phosphorous compounds like pyrantel and morantel.

SIDE EFFECTS:

Overdosing may cause unrest, ataxia, tremors, apathy and paralysis.

DOSAGE AND ADMINISTRATION:

For oral administration via feed or drinking water.

• Broilers:
  Age in weeks          g of Piper Dewormer wsp in 1,000 litres drinking water
  1 – 2                        195 g daily during 2 days
  3 – 4                         270 g daily during 2 days
  5 – 6                         360 g daily during 2 days
  This is equivalent to 32 mg piperazine per kg bodyweight.
• Layers : 760 g Piper Dewormer wsp in 1,000 litres drinking water, daily during 2 days. This dosage is based on layers with a bodyweight of 2,5 kg and a water uptake of 210 ml per animal per day. This is equivalent to 32 mg piperazine per kg bodyweight
• Cattle, horses, pigs : 2,2 g Piper Dewormer wsp per 10 kg bodyweight, equivalent to 110 mg of piperazine base per kg bodyweight.

Anthelmintic activity is directly related to the proportion of free base, which is in Piperazine dihydrochloride 50%. Mixed with feed, the product should be used immediately. Medicated drinking water should be used within 24 hours. Treatment can be repeated within 30 – 45 days.

WITHDRAWAL PERIOD:

• Meat : 3 days
• Eggs : 2 days

Not authorised for use in animals producing milk for human consumption.

STORAGE:

Store in a dry, dark place between 2 °C and 25 °C.
Store in closed packing.
Keep medicine away from children.